Abstract Information 
Abstract ID
20260010
Category
Knee: Miscellaneous
Preferable Presentation
Oral Presentation
Title
SINGLE-STAGE REVISION TOTAL KNEE ARTHROPLASTY IS MORE COST-EFFECTIVE THAN TWO-STAGE REVISION IN THE TREATMENT OF PROSTHETIC JOINT INFECTION
Author
  • Full Name: LOW RENKAI JUSTIN
  • Affiliation/Institution: Singapore General Hospital
  • Country: Singapore

  • Full Name: GARREN PANG
  • Affiliation/Institution: Singapore General Hospital
  • Country: Singapore

  • Full Name: CHIU SHI TING
  • Affiliation/Institution: Singapore General Hospital
  • Country: Singapore

  • Full Name: PANG HEE NEE
  • Affiliation/Institution: Singapore General Hospital
  • Country: Singapore
Presenter
low renkai justin
Abstract
Background:
Chronic periprosthetic joint infection (PJI) following total knee arthroplasty (TKA) is a devastating complication traditionally treated with two-stage revision. Single-stage revision has emerged as a viable alternative in selected patients, but comparative data on outcomes and cost-effectiveness remains limited.
Objective(s):
To compare clinical outcomes and healthcare utilisation between single-stage and two-stage revision total knee arthroplasty (TKA) for chronic prosthetic joint infection (PJI).
Study Design:
A retrospective cohort study was conducted at a tertiary institution. Patients undergoing revision TKA for chronic PJI were identified using institutional databases. Single-stage revision TKA (n = 20) was compared with two-stage revision TKA (n = 57). PJI was diagnosed according to Musculoskeletal Infection Society Criteria. Outcomes assessed included re-revision, functional outcome, inflammatory marker resolution, operative burden, and length of hospital stay.
Results:
Single-stage revision demonstrated comparable—if not superior—clinical outcomes to two-stage revision, with no increase in reinfection or treatment failure. Single-stage revision was associated with fewer surgical procedures, shorter cumulative hospital stay, and faster resolution of inflammatory markers. Functional outcomes were similar between groups among patients with available follow-up data.
Conclusion(s):
Single-stage revision TKA is a viable and more cost-effective alternative to two-stage revision for chronic PJI in appropriately selected patients, achieving comparable clinical outcomes while reducing healthcare burden.